
Probably, there is no woman who would have not faced with this trouble at least once in the life. Itching, irritation, discomfort, and, as a consequence, bad mood and feeling sick. Yeast infection in our time is not a sentence. It can be cured with different remedies, among which is Diflucan.
Diflucan is a commercial name of Fluconazole. Each capsule contains (depending on the supplied form) 50, 100, 150 and 200 mg of fluconazole. Packages with a dosage of 50 and 100 mg contain seven or twenty-eight capsules, but 150-200 mg capsules come as a single dose per box. In addition to fluconazole, each capsule contains some additional neutral substances – lactose, maize starch, colloidal silicon dioxide, magnesium stearate, sodium lauryl sulfate. Diflucan is also available in powder for suspension for oral administration in bottles of 50 ml and a solution for intravenous infusion.
The properties of Diflucan come due to its main component fluconazole: it acts on the fungal cell, increasing the permeability of cell membranes, disrupting its growth and replication. At the same time fluconazole is gentle enough for the liver (in comparison with itraconazole, clotrimazole, econazole, and ketoconazole). Fluconazole penetrates into all fluids of the body. Concentrations of fluconazole in saliva and sputum are the same as in blood plasma. Diflucan is completely excreted by the urine, approximately 80% of the drug is unchanged.
Diflucan is used for many diseases of fungal nature. The drug’s advantage is that the therapy can be started before having the results of culture and other laboratory tests:
- Cryptococcosis
- Generalized candidosis
- Candidiasis of mucous membranes
- Genital candidiasis
- Mycoses of the skin
- Deep endemic mycoses
Diflucan can be used in AIDS, cancer, especially for prevention in the radio-and chemotherapy, as well as to prevent frequent yeast relapses. Diflucan can also be used in children, but only under the supervision of a physician.
The daily dose and in children and adults depends on the nature and severity of fungal infection. In vaginal candidiasis (thrush) in most cases a single dose is effective. In infections requiring repeated administration of the fungal remedy, the treatment should be continued until disappearance of clinical or laboratory signs of active fungal infection.
Administration of Diflucan does not depend on food intake, however it is recommended to take the drug with a full glass of water and to not consume alcoholic drinks during the treatment. A study showed that the repeated use of fluconazole is unlikely to have an influence on the effectiveness of combined oral contraceptive pills.
Contraindications:
- Hypersensitivity to fluconazole or to other azole compounds;
- Concomitant use of terfenadine in patients who receive fluconazole therapy at a dose of 400 mg / day or higher;
- Concomitant use of cisapride;
Tolerability of fluconazole is usually very good. If adverse reactions occur, they usually have a gastrointestinal nature: nausea, abdominal pain, diarrhea, and flatulence; sometimes rash and headache. There are knows some cases of anaphylactic reactions, then the Duflucan therapy should be stopped immediately. Clinical experience with fluconazole shows that fluconazole does not affect the driving ability and other activities.